M1 Neuro - Teaching Program

Semester 1 provides solid foundations in the fields of physiology and neurophysiology both in terms of fundamental knowledge and experimental (and analytical) practices. In addition to a 6-week internship, semester 2 offers the student a choice of teaching units allowing him/her to specialize and deepen his/her specific knowledge, from molecular neurobiology to integrated, cognitive, and clinical neurosciences. This format allows the student to prepare more specifically for one of the two Master courses offered in the second year.

First Semester

Disciplinary Courses

Scientific Tools

Physiologie et Neurosciences Intégratives

In this teaching unit, physiology and integrative neurosciences are illustrated through the study of “nutrition”, with its different neural, metabolic and behavioural components. The objective of the unit is to give to the students a broad and integrative view of this physiological function and to address the main nutritional pathologies.

More info: PNI
Responsable/s: Claude DUCHAMP (claude.duchamp@univ-lyon1.fr) & Karyn JULLIARD (karyn.julliard@univ-lyon1.fr)

Différenciation et Physiologie des Cellules Excitables

Nerve cells have a close functional relationship with skeletal muscle cells. This relationship is established through the differentiation of these two cell types. The teaching unit addresses these differentiation processes during pre- and post-natal development, focusing on electrophysiological propagation and synaptic transmission in the motor system. Related pathologies are also discussed.

More info: Diphex

Responsable/s: Corine AMAT (corine.amat@univ-lyon1.fr) & Christine BERTHIER (christine.berthier@univ-lyon1.fr)

Neurosciences Cognitives et Imagerie Cérébrales

This teaching unit comprises an introduction to Cognitive Neuroscience with lectures dedicated to several high-level functions, such as attention, memory, and decision making in human and non-human primates. The unit has a strong methodological component that allows the students to acquire some basic programming skills and to familiarise with the analysis of fMRI, PET and EEG data. Teaching is in English and French.

More info: NeuroCO

Responsable/s: Emiliano MACALUSO (emiliano.macaluso@univ-lyon1.fr)

Pratiques Expérimentales en Physiologie et Neurosciences

In this unit, exclusively composed of practical work and tutorials, students will apply the knowledge acquired in the mandatory units of semester 1 and will acquire specific skills. The students choose 2 themes from: 1) Nerve functional differentiation: role of different modulating factors (cell culture); 2) Excitability and neural networks : spontaneous discharge activity of a neuron within its network and pharmacological modulation of this network (electrophysiology practice-intracellular recording- and thalamo-cortical loop computer model); 3) Brain imaging: data processing and analysis for several imaging modalities (PET, fMRI, EEG, MEG).

More info: PrEx

Responsable/s: Véronique PELLIER-MONNIN (veronique.pellier-monnin@univ-lyon1.fr) & Christine BERTHIER (christine.berthier@univ-lyon1.fr)

Méthodologie, Statistiques, Communication Scientifique

The teaching unit has three main components. The objective of the first component is to introduce the main principles of the scientific approach (epistemology). The second component focuses on basic statistics (parametric/non-parametric, introduction to the software “R”). The aim of the third component is to make the students aware of the importance of scientific communication, and to train them in writing and presenting scientific results.
 
More info: MethCom
Responsable/s: DUCHAMP CLAUDE (claude.duchamp@univ-lyon1.fr) & Philippe BOULINGUEZ (philippe.boulinguez@univ-lyon1.fr)

Second Semester

Disciplinary Courses

Scientific Tools

Physiologie des Réseaux Neuronaux

The aim of the unit is to provide an in-depth description of the mechanisms underlying the functioning of neural networks, specifically in relation to cognitive functions. This entails examining cellular mechanisms at the level of the neuron/synapse, as well as macroscopic processes governing inter-regional communication at the whole brain level. Examples from a broad range of functions (learning, sleep, olfaction, action control, language…) will serve to illustrate the main methods for studying the physiology of neural networks in the human and non-human brain.

More info: Réseaux

Responsable/s: Corine AMAT (corine.amat@univ-lyon1.fr)

Neurobiologie du Comportement

This unit presents the neural basis of behavior and methodologies allowing linking neuronal activity or cellular events to behaviour. An emphasis is given to the contribution of animal models to the understanding of neural mechanisms underlying behavior.

More info: NBC

Responsable/s: Anne DIDIER (anne.didier@univ-lyon1.fr)

Neuroplasticité et Neuropathologies

This unit targets cellular and molecular dysfunctions of the central nervous system, specifically in relation to neurodegenerative pathologies and brain plasticity. The unit examines processes and factors determining changes in the nervous system in the context of normal and pathological aging.

More info: N2P2

Responsable/s: Véronique PELLIER-MONNIN (veronique.pellier-monnin@univ-lyon1.fr)

Anglais pour la communication professionnelle niveau 1

English course focusing on oral and written communication in the field of Neurosciences. Training comprises the writing of reports and articles, as well as the presentation and discussion of scientific results, both in formal (e.g. conferences) and informal (e.g. lab meetings) situations.

More info: Anglais

Responsable/s: Nathalie DOURLOT (nathalie.dourlot@univ-lyon1.fr)

Formation Humaine

The aim of this teaching unit is to help the student to construct and pursue a professional project. This includes training in writing CVs, motivation letters and passing interviews. Within the same unit is also possible to participate to the design of a “communication project” with the tutoring of a teacher. For example, the project may entail the organization of a scientific conference, of a meeting between academics and industrial partners, or the presentation of a initiative in the field of preventive medicine.

More info: FH

Responsable/s: Anne VIANNEY (anne.vianney@univ-lyon1.fr) & Brigitte PAULIGNAN (brigitte.paulignan@univ-lyon1.fr)

Stage

The aim of this 6-weeks internship is to initiate the students to neuroscience research in the laboratory. The students participate to ongoing projects, contributing to data acquisition and analyses. The writing-up of the internship report and the subsequent oral defense enable the training of key scientific communication skills. The internship is also an excellent opportunity to start making professional contact with the neuroscience research network.

More info: Stage

Responsable/s: Corine AMAT (corine.amat@univ-lyon1.fr) & Christine BERTHIER (christine.berthier@univ-lyon1.fr)

Optional Units

Métrologie Sensorielle

This teaching unit is an introduction on how neurosciences knowledge and methods can be applied to companies.  The unit offers the chance to run an experiment in sensorial analysis using eye tracking. Also, the unit benefits of external experts’ interventions: from companies and academia, to help students to better understand which tools and answers neurosciences can provide to different sensory analysis domains.

More info: MetroSens

Responsable/s: Irene CRISTOFORI (irene.cristofori@univ-lyon1.fr)

De la Molécule à la Mémoire

This teaching unit illustrates the power of multi-level analysis to understand brain function. Based on the example of fear memory, lectures cover the different levels of analysis used in Neurosciences: from molecular and cellular neurobiology to synaptic plasticity, brain network remodelling and behavior. A student’s personal bibliographic search will complement the lectures.

More info: MOMEM

Responsable/s: Marion RICHARD (marion.richard@univ-lyon1.fr)

Neurosciences Computationnelles

The aim of this unit is to lay the theoretical and methodological foundations for investigation in the field of computational neuroscience. The courses will first discuss the main theoretical, historical and philosophical principles of computational modeling, and introduce some applications (robotics, artificial intelligence, expert systems, etc.). Next, relevant mathematical approaches will be presented, including simple differential equations, Bayesian statistics, neuronal simulations, as well as some introduction to machine learning. Practical courses will target, on the one hand, the modeling of behavioral and cognitive processes and, on the other hand, the modeling of neurons and neuronal networks. This unit is funded by the CRNL and the LabEx CORTEX.

More info: Neurosc Compt

Responsable/s: Corine AMAT (corine.amat@univ-lyon1.fr) & Jérémie MATTOUT (jeremie.mattout@inserm.fr)

Elaboration de Projets Scientifiques

More info: EPS

Responsable/s: Karyn JULLIARD (karyn.julliard@univ-lyon1.fr) & Caroline ROMESTAING (caroline.romestaing@univ-lyon1.fr)

Immunité

More info: Immunité

Responsable/s: Mathias FAURE (mathias.faure@inserm.fr)

Neuropsychologie

The aim of this unit  is to link knowledge about the normal vs. deficient cognitive system by presenting specific pathologies that may help in understanding the functioning of human cognition as a whole. The unit is part of the Master “Cognitive Psychology and Neuropsychology” of the Université Lumière Lyon 2.

More info: Neuropsycho

Responsable/s: Corine AMAT (corine.amat@univ-lyon1.fr) & Pascale COLLIOT (pascale.colliot@univ-lyon2.fr)